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Polycystic kidney disease (PKD) is a lifelong, genetic disease, that worsens over time as fluid-filled cysts form and enlarge both kidneys, often leading to kidney failure.
ADPKD is the ‘adult’ form of PKD and one of the most common genetic diseases. There is usually a family history of ADPKD with parents having a 50% chance of passing the disease on to each of their children. It does not skip a generation. Many of those affected may experience regular pain and high blood pressure while over half may develop kidney failure by the time they are 60 years old.
ARPKD is the ‘infantile’ form of PKD and a relatively rare form that is usually diagnosed at birth and affects approximately 1 in 20,000 individuals. It usually presents as enlarged kidneys with no family history of kidney disease. Boys and girls are affected equally however, both parents need to carry the gene defect for the child to inherit the disease.
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